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Showing posts from October, 2024

Histopathological Techniques and Their Importance in Diagnosis

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Histopathology, the microscopic examination of tissue to study the manifestations of disease, plays a crucial role in medical diagnostics . Through various staining and visualization techniques, pathologists can accurately diagnose a wide array of diseases, from infections to cancers. Each histopathological method provides unique insights, making it indispensable in understanding disease mechanisms and guiding patient treatment. What is Histopathology ? Histopathology involves the preparation, staining, and examination of tissue samples under a microscope . The tissue can be obtained from a biopsy, surgical resection, or post-mortem examination. By evaluating the structural changes within cells and tissues, pathologists can identify abnormalities and make definitive diagnoses. The process typically begins with fixation to preserve tissue integrity, followed by embedding , sectioning , and staining . Once stained, the tissue is examined under a microscope to detect disease pa

Molecular Diagnostics in Pathology: Revolutionizing Disease Diagnosis and Personalized Medicine

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The field of pathology is undergoing a remarkable transformation, driven by the integration of molecular diagnostics. This evolving discipline has redefined the way pathologists diagnose diseases, enabling a shift toward more precise, personalized, and predictive medicine. From cancer genotyping to infectious disease detection, molecular diagnostics is helping pathologists unlock deeper insights into the molecular makeup of diseases. But what exactly is molecular diagnostics, and how is it reshaping the landscape of pathology? What is Molecular Diagnostics ? Molecular diagnostics refers to a set of laboratory techniques used to analyze DNA, RNA, proteins, and other molecules to detect specific genetic sequences, mutations, or biomarkers in tissues and bodily fluids. By examining these molecular components, pathologists can provide highly accurate diagnoses and prognoses, predict treatment responses, and even identify disease predispositions. Unlike traditional methods, which rely heavi